Profile (Nadrolone decanoate)
First of all, Deca (and Nandrolone in general) does not produce many estrogenic or androgenic side effects. This is because Deca has a rate of aromatization (conversion to estrogen via the aromatase enzyme) very low, approximately equal to the rate of testosterone (20%).
In addition, many articles claim that Deca stores water in connective tissue, relieving joint pain. I have no idea where these statements came out, or when they started. However, in a study of menopausal women, Deca improved collagen synthesis (1) and, in another study, Deca increased bone mineral content (2).Both studies used very low doses that were too low to promote muscle growth.Based on these two studies, the athlete to use Deca only for these two effects (increased bone mineral content and collagen synthesis) should use 100mg of Deca a week. This is actually a higher dose than used in these two successfully.Even with half that dose, one injection of 100mg every two weeks, HIV-positive patients experienced a significant weight gain (5). Not recommended as low a dose for an athlete, but this proves the strong anabolic properties of Deca. Deca is an excellent anabolic, causing nice (albeit slow) gains in quality muscle. One of its effects is nitrogen retention, which is an important factor in muscle growth and lean mass gains. In a study with low doses (65 mg / week) and median doses of Deca (200 mg / week), both resulted in significant nitrogen retention (33-52 g nitrogen in 14 days, representing gains of 0.5 to 0, 9 kg of lean per week). Body weight increased 4.9 + / - 1.2 kg, including 3.1 + / - 0.5 kg of lean body mass and performance in exercises (cardiovascular fitness) also improved (7). Need I say that higher doses in this study produced greater gains? The recommendation for mass gain is around 400 to 600 mg per week (on average).
Deca also has a long active life. With an application of Deca, nandrolone levels will be stable in plasma for about 10 days, so it is recommended each application at least 7 days in order to maintain these levels stable throughout the cycle.Interestingly too, it was perceived higher levels of nandrolone in plasma with applications in the buttocks, unlike what happens with applications on the deltoids. (This goes for all oil-based steroids).
In another study of HIV + men (6) we can see that deca (200mgs on week 1, 400mg at week 2 and 600mgs weeks 3-12) caused no negative side effects on total cholesterol or LDL, triglycerides and insulin sensitivity and there was a reduction in HDL cholesterol (8-10 points) in both groups. Moreover, in most studies with HIV +, Deca also improved immune function. So what we know so far about this compound? So far, we know that Deca is a very safe drug for use in the long run will contribute to common problems, could improve immune function, and is highly (!) And not very androgenic anabolic. That's the good news ... Now for the bad part ...
Deca is known for producing weight gains, but must be used for 12 weeks minimum (by American standards). This should not cause any problems, since it is a very mild drug in terms of side effects. Many users also complain of water retention with this drug. Letrozole seems to be the preferred option to address this problem. This water retention is one of Deca more suitable for bulking drug, although it can be successfully used for cutting too. Now the worst news: Deca is a progestin (as are all nandrolone). This means that it will stimulate the progesterone receptor 20% more, as well as progesterone itself (3), and this opens the door to many unwanted side effects (retention, acne, etc.).. It should be noted that most of these are rare, though. This can also be the main reason why Deca is such a suppressive drug when it comes to your natural testosterone levels. A single dose of 100mg of Deca causes a full (100%) reduction of natural testosterone levels, and takes about a month so that these levels return to normal!All because of mere 100mg of Deca ...
Moral of the story? Always use testosterone and Deca! At least 250mg per week, to avoid impotence and sexual dysfunction. For an anabolic effect with testosterone, at least double that, with equal amount of Deca (minimum). It is also recommended taking an anti-progesterone (or at least have it on hand): Bromocriptine or cabergoline are good choices. Well, it is comfortable recommending the use of Deca in doses up 600mg/semana for a long period (12-16 weeks), or cutting cycles with 400mg/semana (again, for 12-16 weeks), along with something to combat water retention. Whatever purpose you decide to use, still need to include testosterone in your cycle and have some anti-progesterone drugs in hand, just in case.
The post-cycle therapy (PCT), although outside the scope of this profile, you have to be addressed. Due to the highly suppressive nature of Deca, the administration of testosterone in a cycle of Deca should be run for at least 2 additional weeks upon cessation of Deca. Remember that testosterone levels take about a month to normalize. Thus, a long ester testosterone should be administered for about two weeks beyond the last application of Deca, to prevent having a lag in time that Deca no longer produces an anabolic effect, yet is still suppressing your natural testosterone production . We also recommend the use of HCG at least in the last weeks of the cycle, and a TPC with tamoxifen and Tribulus terrestris, using every effort to restore testosterone levels more quickly and efficiently as possible.
Buy this drug (Organon) in pharmacy is much more reliable, but also much more expensive. You will pay on average $ 15.00 on 50mg of the drug, this is getting a prescription. Underground labs produce drugs with dosage 200-250mg/ml, plugs into 10 ml each. The price is lower (compared mg for mg), will cost about $ 150.00 to $ 200.00.
Nandrolone decanoate - C18 H26 O2
Molecular Weight: 274.4022
Half-Life: 15 days
Administration: Intra-Muscular
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References:
1. Metabolism. 1990 Nov; 39 (11) :1167-9
2. Effects of nandrolone decanoate on bone mineral content R, Righi GA, Turchetti V, Vattimo A.).
3. Cancer Res 1978 Nov; 38 (11 Pt 2) :4186-98
4. (Charts) from Minto et al
5.AIDS. 1996 Jun; 10 (7) :745-52
6.Sattler et al. Am J Physiol Endocrinol Metab 283: e1214-22
7. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Feb 1; 20 (2) :137-46.
